Why studies that rely too much on drugs often fail to hold up

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Scientists constantly wrestle with internal conflicts. Mine? I’m a reluctant pharmacologist. Even though I’m trained to develop medications, I don’t like to use them in my own research. I prefer to focus on a more basic question: what unique features of diseased cells can we take advantage of to design better drugs? We need to make sure to minimize the uncertainty in research, and using pharmacological agents to study cells only contributes to it because...

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