TET1 protein helps prevent congenital defects and late-onset diseases

In the earliest stages of embryonic development, a protein known as TET1 may be the factor that tips the balance toward health or disease. The first evidence for this vital role of TET1 is presented in Nature Genetics by researchers from KU Leuven (University of Leuven), Belgium. They found that TET1 is necessary to prevent congenital defects such as spina bifida as well as mental retardation and cancer later in life.

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