NIH researchers crack mystery behind rare bone disorder

Researchers at the National Institutes of Health worked with 15 patients from around the world to uncover a genetic basis of 'dripping candle wax' bone disease. The rare disorder, known as melorheostosis, causes excess bone formation that resembles dripping candle wax on x-rays. The results, appearing in Nature Communications, offer potential treatment targets for this rare disease, provide important clues about bone development, and may lead to insights about fracture healing and osteoporosis.

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