Modular gene enhancer promotes leukemia and regulates effectiveness of chemotherapy

Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer. Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM have now found that just how big a role Myc plays is determined by a distant section of DNA that contains a cluster of gene enhancers.

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